Baeten, D. et al. (2005) Synovial tissue analysis in clinical trials. Journal of Rheumatology, 32, pp. 2481-2484. (PMID:16331792)
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Publisher's URL: http://www.jrheum.org/content/32/12/2481.abstract
Abstract
Synovial tissue analysis has considerable potential for future randomized controlled trials (RCT). The synovial membrane is the target tissue in treatment strategies of rheumatoid arthritis and other arthropathies. Effective modulation of synovitis is critical when attempting to control symptoms and signs, to prevent joint damage, and to maintain function. In RCT, the systematic evaluation of changes in synovial tissue after commencing treatment enables identification of an early therapeutic effect, using relatively small numbers of patients. This special interest group is working on establishing the evidence to have this endpoint meet the OMERACT filter criteria.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | McInnes, Professor Iain |
| Authors: | Baeten, D., Bresnihan, B., Firestein, G., Fitzgerald, O., Gerlag, D., Haringman, J., McInnes, I., Reece, R., Smith, M., Tak, P., Ulfgren, A., and Veale, D. |
| College/School: | College of Medical Veterinary and Life Sciences College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Journal of Rheumatology |
| Publisher: | Journal of Rheumatology |
| ISSN: | 0315-162X |
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