Cognitive functioning in a representative cohort of preschool children with febrile seizures

Billstedt, E., Nilsson, G., Leffler, L., Carlsson, L., Olsson, I., Fernell, E. and Gillberg, C. (2020) Cognitive functioning in a representative cohort of preschool children with febrile seizures. Acta Paediatrica, 109(5), pp. 989-994. (doi: 10.1111/apa.15059) (PMID:31618476)

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Abstract

Aim: To analyse cognitive functioning in 4‐5‐year‐old children who had experienced febrile seizures (FS) and to assess the importance of complex, recurrent and early vs late onset FS. Methods: The sample consisted of 73 children, screen positive for FS, drawn from the general child population of 4‐year‐old children attending their health check‐up at child healthcare centres in Gothenburg, Sweden. They were assessed as regards general cognitive ability, visual memory and attention and were contrasted with age norms and with results obtained in 20 children without FS from the same healthcare centres. Results: Of the 73 children, two had a previously diagnosed intellectual disability (ID) (one mild, one moderate) and two further children tested within the study had results corresponding to mild ID. Children with early onset of FS (before age 12 months)—who often had recurrent FS—had lower full‐scale, verbal and processing speed IQ than those who had later onset of FS. Conclusion: Children with early onset of FS and particularly those with recurrent FS may be at increased risk for poorer verbal and processing speed functioning and therefore at risk of developing cognitive, executive dysfunctions. They would probably benefit from neuropaediatric and neuropsychological follow‐up.

Item Type:Articles
Additional Information:Funding Information: Local Research and Development Council of the Västra Götaland Region ; Linnea and Josef Carlsson foundation ; Per and Ann‐Marie Ahlqvist Foundation.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Gillberg, Professor Christopher
Authors: Billstedt, E., Nilsson, G., Leffler, L., Carlsson, L., Olsson, I., Fernell, E., and Gillberg, C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Mental Health and Wellbeing
Journal Name:Acta Paediatrica
Publisher:Wiley
ISSN:1651-2227
ISSN (Online):1651-2227
Published Online:10 November 2019

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