Biomarkers of vascular inflammation and cardiovascular disease

Welsh, P. , Preiss, D. , Tsiropoulou, S., Rios, F. J. , Harvey, A., Dulak-Lis, M. G., Montezano, A. C. and Touyz, R. M. (2015) Biomarkers of vascular inflammation and cardiovascular disease. In: Berbari, A. and Mancia, G. (eds.) Arterial Disorders: Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches. Springer: Cham, pp. 115-136. ISBN 9783319145556 (doi:10.1007/978-3-319-14556-3_9)

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Abstract

Cardiovascular disease is the major cause of morbidity and mortality globally. As such better approaches for early detection and mechanism-targeted therapies are key priorities in cardiovascular research. Growing evidence indicates that vascular inflammation and oxidative stress may play an important role in the genesis and progression of cardiovascular disease. Accordingly identification of markers reflecting these processes may be useful early predictors of vascular damage and could provide insights into mechanisms, risk and targeted treatment. The present chapter provides a brief overview of vascular damage in cardiovascular disease and discusses recently identified novel biomarkers of vascular inflammation and oxidative stress. The potential clinical relevance is also highlighted.

Item Type:Book Sections
Status:Published
Glasgow Author(s) Enlighten ID:Rios, Dr Francisco and Tsiropoulou, Miss Sofia and Preiss, Dr David and Dulak-Lis, Ms Maria and Harvey, Dr Adam and Montezano, Dr Augusto and Welsh, Dr Paul and Touyz, Professor Rhian
Authors: Welsh, P., Preiss, D., Tsiropoulou, S., Rios, F. J., Harvey, A., Dulak-Lis, M. G., Montezano, A. C., and Touyz, R. M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Publisher:Springer
ISBN:9783319145556

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