Role of interleukin 15 and interleukin 18 in inflammatory response

Liew, F. and McInnes, I. (2002) Role of interleukin 15 and interleukin 18 in inflammatory response. Annals of the Rheumatic Diseases, 61, pp. 100-102. (doi:10.1136/ard.61.suppl_2.ii100) (PMID:12379638) (PMCID:PMC1766710)

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Abstract

Interleukin 15 (IL15) and interleukin 18 (IL18) are cytokines produced principally by macrophages during innate immune response and subsequently profoundly influence adaptive immunity. Recent studies have shown that IL15 and IL18 play an influential part in inflammatory response. Here we present recent data mainly from our own laboratories illustrating the importance of IL15 and IL18 in the induction and perpetuation of chronic inflammation during experimental and clinical rheumatoid synovitis.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McInnes, Professor Iain and Liew, Professor Foo
Authors: Liew, F., and McInnes, I.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Annals of the Rheumatic Diseases
Publisher:B M J Group
ISSN:0003-4967
ISSN (Online):1468-2060

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