Rapid additive-free bacteria lysis using traveling surface acoustic waves in microfluidic channels

Lu, H., Mutafopulos, K., Heyman, J. A., Spink, P., Shen, L., Wang, C., Franke, T. and Weitz, D. A. (2019) Rapid additive-free bacteria lysis using traveling surface acoustic waves in microfluidic channels. Lab on a Chip, 19(24), pp. 4064-4070. (doi: 10.1039/C9LC00656G) (PMID:31690904)

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Abstract

We introduce a microfluidic device that uses traveling surface acoustic waves to lyse bacteria with high efficiency. This lysis method should be applicable to a wide range of bacteria species and can be modified to analyze individual bacteria cells.

Item Type:Articles
Additional Information:This work was supported by the NSF (DMR-1708729) and the Harvard MRSEC (DMR-1420570). The fabrication was performed at the Harvard Center for Nanoscale Systems (CNS), a member of the National Nanotechnology Infrastructure Network (NNIN), which is supported by the National Science Foundation under NSF award no. ECS-1541959.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Franke, Professor Thomas
Authors: Lu, H., Mutafopulos, K., Heyman, J. A., Spink, P., Shen, L., Wang, C., Franke, T., and Weitz, D. A.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Lab on a Chip
Publisher:Royal Society of Chemistry
ISSN:1473-0197
ISSN (Online):1473-0189
Published Online:30 October 2019

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