Delirium in an acute stroke setting, occurrence, and risk factors

Shaw, R., Drozdowska, B. , Taylor-Rowan, M. , Elliott, E., Cuthbertson, G., Stott, D. J. and Quinn, T. J. (2019) Delirium in an acute stroke setting, occurrence, and risk factors. Stroke, 50(11), pp. 3265-3268. (doi: 10.1161/strokeaha.119.025993) (PMID:31554500)

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Abstract

Background and Purpose— Delirium is a common and serious complication of acute illness. We describe delirium occurrence in an unselected, acute stroke population. Methods— We collected data from consecutive stroke admissions. We performed comprehensive cognitive assessment within the first week including Diagnostic Statistical Manual-5–based delirium diagnosis. We reported proportion with delirium and the clinical and demographic associations with delirium using multiple logistic regression. Results— Of 708 patients, median age of 71 years (interquartile range, 59–80), we recorded delirium in 187 of 708 (26.4%; 95% CI, 23.0–30.0). Across 395 patients with complete risk factor data (105 delirium), factors independently associated with delirium were: age (odds ratio, 1.05; 95% CI, 1.03–1.08), drug/alcohol misuse (odds ratio, 2.64; 95% CI, 1.10–6.26), and stroke severity (odds ratio, 1.22; 95% CI, 1.14–1.31). Conclusions— Delirium is common in acute stroke, affecting 1 in 4. It may be possible to predict those at risk using prestroke and stroke-specific factors. Clinical Trial Registration— URL: researchregistry.com. Protocol: 1147.

Item Type:Articles
Additional Information:Dr Quinn is supported by Stroke Association/Chief Scientist Office; Dr Stott reports grant funding from the European Union.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Taylor-Rowan, Mr Martin and Elliott, Emma and Stott J, Professor David and Drozdowska, Bogna and Shaw, Mr Robert and Quinn, Dr Terry
Authors: Shaw, R., Drozdowska, B., Taylor-Rowan, M., Elliott, E., Cuthbertson, G., Stott, D. J., and Quinn, T. J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Stroke
Publisher:American Heart Association
ISSN:0039-2499
ISSN (Online):1524-4628
Published Online:26 September 2019
Copyright Holders:Copyright © 2019 American Heart Association, Inc.
First Published:First published in Stroke 50(11):3265-3268
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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