The role of innate mediators in inflammatory response

Liew, F. and McInnes, I. (2002) The role of innate mediators in inflammatory response. Molecular Immunology, 38, pp. 887-890. (doi:10.1016/S0161-5890(02)00014-7) (PMID:12009565)

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Abstract

Cytokines produced by innate immune response can profoundly influence the subsequent adaptive immunity. IL-15 and -18 are two of several mediators produced by macrophages that perform such a function. Here we present recent data mainly from our own laboratory illustrating the important role of IL-15 and -18 in the induction and perpetuation of chronic inflammation during experimental and clinical rheumatoid synovitis.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McInnes, Professor Iain and Liew, Professor Foo
Authors: Liew, F., and McInnes, I.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Molecular Immunology
Publisher:Elsevier
ISSN:0161-5890

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