Fueling regulation: IL-2 keeps CD4+ Treg cells fit

Maloy, K. J. and Powrie, F. (2005) Fueling regulation: IL-2 keeps CD4+ Treg cells fit. Nature Immunology, 6(11), pp. 1071-1072. (doi: 10.1038/ni1105-1071) (PMID:16239920)

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Abstract

Naturally occurring regulatory T cells are key in controlling autoimmune and inflammatory responses. New data indicate that although interleukin 2 signals are not essential for regulatory T cell development in the thymus, they are critical for maintenance of these cells in the periphery.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Maloy, Professor Kevin
Authors: Maloy, K. J., and Powrie, F.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Nature Immunology
Publisher:Nature Publishing Group
ISSN:1529-2908
ISSN (Online):1529-2916

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