Scene representations conveyed by cortical feedback to early visual cortex can be described by line drawings

Morgan, A. T., Petro, L. S. and Muckli, L. (2019) Scene representations conveyed by cortical feedback to early visual cortex can be described by line drawings. Journal of Neuroscience, 39(47), pp. 9410-9423. (doi: 10.1523/JNEUROSCI.0852-19.2019) (PMID:31611306) (PMCID:PMC6867807)

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Abstract

Human behavior is dependent on the ability of neuronal circuits to predict the outside world. Neuronal circuits in early visual areas make these predictions based on internal models that are delivered via non-feedforward connections. Despite our extensive knowledge of the feedforward sensory features that drive cortical neurons, we have a limited grasp on the structure of the brain's internal models. Progress in neuroscience therefore depends on our ability to replicate the models that the brain creates internally. Here we record human fMRI data while presenting partially occluded visual scenes. Visual occlusion allows us to experimentally control sensory input to subregions of visual cortex while internal models continue to influence activity in these regions. Since the observed activity is dependent on internal models, but not on sensory input, we have the opportunity to map visual features conveyed by the brain's internal models. Our results show that activity related to internal models in early visual cortex are more related to scene-specific features than to categorical or depth features. We further demonstrate that behavioral line drawings provide a good description of internal model structure representing scene-specific features. These findings extend our understanding of internal models, showing that line drawings provide a window into our brains' internal models of vision.

Item Type:Articles
Additional Information:This project has received funding from the European Union’s Horizon 2020 Programme for Research and Innovation under the Specific Grant Agreement No. 720270 and 785907 (Human Brain Project SGA1 and SGA2), and the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme under grant agreement No ERC StG 2012_311751-‘Brain reading of contextual feedback and predictions’ awarded to LM.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Morgan, Mr Andrew and Petro, Dr Lucy and Muckli, Professor Lars
Authors: Morgan, A. T., Petro, L. S., and Muckli, L.
College/School:College of Medical Veterinary and Life Sciences > Institute of Neuroscience and Psychology
Journal Name:Journal of Neuroscience
Publisher:The Society for Neuroscience
ISSN:0270-6474
ISSN (Online):1529-2401
Published Online:14 October 2019
Copyright Holders:Copyright © 2019 The Authors
First Published:First published in Journal of Neuroscience 39(47): 9410-9423
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
172779Human Brain ProjectLars MuckliEuropean Commission (EC)Muckli, Professor LarsNP - Centre for Cognitive Neuroimaging (CCNi)
304518Human Brain Project SGA 2Lars MuckliEuropean Commission (EC)N/ANP - Centre for Cognitive Neuroimaging (CCNi)