Baeten, D., Bresnihan, B., Fitzgerald, O., McInnes, I. , Smith, M., Tak, P., Ulfgren, A. and Veale, D. (2006) Standardisation of synovial tissue infiltrate analysis: how far have we come? how much further do we need to go? Annals of the Rheumatic Diseases, 65, pp. 93-100. (doi: 10.1136/ard.2005.036905) (PMID:15975970) (PMCID:PMC1797968)
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Abstract
Changes in cellular infiltrate and expression of cytokines, chemokines, and cell adhesion molecules as a result of therapeutic interventions in rheumatoid arthritis can be demonstrated in the synovial membrane. However, before synovial tissue analysis can be used as an outcome measure in such studies, standardisation of the site and method of synovial tissue acquisition, methods of tissue processing, and appropriate methods of detection and measurement of cell lineage specific markers and relevant biological proteins is needed.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | McInnes, Professor Iain |
Authors: | Baeten, D., Bresnihan, B., Fitzgerald, O., McInnes, I., Smith, M., Tak, P., Ulfgren, A., and Veale, D. |
College/School: | College of Medical Veterinary and Life Sciences College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Annals of the Rheumatic Diseases |
Publisher: | B M J Group |
ISSN: | 0003-4967 |
ISSN (Online): | 1468-2060 |
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