Resurgence of ebola virus disease in Guinea linked to a survivor with virus persistence in seminal fluid for more than 500 days

Diallo, B. et al. (2016) Resurgence of ebola virus disease in Guinea linked to a survivor with virus persistence in seminal fluid for more than 500 days. Clinical Infectious Diseases, 63(10), pp. 1353-1356. (doi: 10.1093/cid/ciw601) (PMID:27585800) (PMCID:PMC5091350)

Abstract

We report on an Ebola virus disease (EVD) survivor who showed Ebola virus in seminal fluid 531 days after onset of disease. The persisting virus was sexually transmitted in February 2016, about 470 days after onset of symptoms, and caused a new cluster of EVD in Guinea and Liberia.

• Item Type: Articles
• Additional Information: This work was carried out in the context of the projects EVIDENT (Ebola virus disease: correlates of protection, determinants of outcome, and clinical management) and REACTION! that received funding from the European Union's Horizon 2020 research and innovation program under grant agreements 666100 (to S. G.) and 666092 (to D. M.), respectively, and in the context of service contract IFS/2011/272-372 (to S. G.) funded by the Directorate-General for International Cooperation and Development. The study was further supported by grant C15-101 from the French Institute of Health and Medical Research (INSERM) to D. S. Work at the University of Makeni was supported by funding from the Wellcome Trust to I. G. (097997/Z/11/A).
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Cotten, Professor Matthew
• Authors: Diallo, B., Sissoko, D., Loman, N. J., Bah, H. A., Bah, H., Worrell, M. C., Conde, I. S., Sacko, R., Mesfin, S., Loua, A., Kalonda, J. K., Erondu, N. A., Dahl, B. A., Handrick, S., Goodfellow, I., Meredith, L. W., Cotten, M., Jah, U., Guetiya Wadoum, R. E., Rollin, P., Magassouba, N.’F., Malvy, D., Anglaret, X., Carroll, M. W., Aylward, R. B., Djingarey, M. H., Diarra, A., Formenty, P., Keïta, S., Günther, S., Rambaut, A., and Duraffour, S.
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity; College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
• Journal Name: Clinical Infectious Diseases
• Publisher: Oxford University Press
• ISSN: 1058-4838
• ISSN (Online): 1537-6591
• Published Online: 01 September 2016
• Copyright Holders: Copyright © 2016 The Authors
• First Published: First published in Clinical Infectious Diseases 63(10):1353–1356
• Publisher Policy: Reproduced under a Creative Commons License