Computational Analysis of the Influence of Dissolution-Diffusion and Specific Binding on Drug Transport in the Arterial Wall following Stent-based Delivery

Escuer, J., Pena, E., Mcginty, S. and Martinez, M. A. (2018) Computational Analysis of the Influence of Dissolution-Diffusion and Specific Binding on Drug Transport in the Arterial Wall following Stent-based Delivery. VII Jornada de Jóvenes Investigadores del (I3A), Zaragoza, Spain, 8 June 2018. (Unpublished)

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Abstract

A computational model of the transport of drugs eluted from a drug-eluting stent (DES) in the arterial wall is developed to study the influence of considering a non-linear model of dissolution-diffusion in the polymeric strut coating of the stent and a non-linear saturable reversible reaction model in the tissue to describe drug specific and non-specific binding.

Item Type:Conference or Workshop Item
Status:Unpublished
Refereed:Yes
Glasgow Author(s) Enlighten ID:Mcginty, Dr Sean
Authors: Escuer, J., Pena, E., Mcginty, S., and Martinez, M. A.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
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