Das, R. , Moradi, F. and Heidari, H. (2020) Biointegrated and wirelessly powered implantable brain devices: a review. IEEE Transactions on Biomedical Circuits and Systems, 14(2), pp. 343-358. (doi: 10.1109/TBCAS.2020.2966920) (PMID:31944987)
|
Text
194197.pdf - Published Version Available under License Creative Commons Attribution. 5MB |
Abstract
Implantable neural interfacing devices have added significantly to neural engineering by introducing the low-frequency oscillations of small populations of neurons known as local field potential as well as high-frequency action potentials of individual neurons. Regardless of the astounding progression as of late, conventional neural modulating system is still incapable to achieve the desired chronic in vivo implantation. The real constraint emerges from mechanical and physical diffierences between implants and brain tissue that initiates an inflammatory reaction and glial scar formation that reduces the recording and stimulation quality. Furthermore, traditional strategies consisting of rigid and tethered neural devices cause substantial tissue damage and impede the natural behaviour of an animal, thus hindering chronic in vivo measurements. Therefore, enabling fully implantable neural devices, requires biocompatibility, wireless power/data capability, biointegration using thin and flexible electronics, and chronic recording properties. This paper reviews biocompatibility and design approaches for developing biointegrated and wirelessly powered implantable neural devices in animals aimed at long-term neural interfacing and outlines current challenges toward developing the next generation of implantable neural devices.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Heidari, Professor Hadi and Das, Dr Rupam |
| Authors: | Das, R., Moradi, F., and Heidari, H. |
| College/School: | College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering |
| Journal Name: | IEEE Transactions on Biomedical Circuits and Systems |
| Publisher: | IEEE |
| ISSN: | 1932-4545 |
| ISSN (Online): | 1932-4545 |
| Published Online: | 15 January 2020 |
| Copyright Holders: | Copyright © 2020 The Authors |
| First Published: | First published in IEEE Transactions on Biomedical Circuits and Systems 14(2):343-358 |
| Publisher Policy: | Reproduced under a Creative Commons license |
University Staff: Request a correction | Enlighten Editors: Update this record
Funder and Project Information
Funder and Project Information