Addressing gaps in care of people with conditions affecting sex development and maturation

Hiort, O. et al. (2019) Addressing gaps in care of people with conditions affecting sex development and maturation. Nature Reviews Endocrinology, 15, pp. 615-622. (doi: 10.1038/s41574-019-0238-y) (PMID:31406344)

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Differences of sex development are conditions with discrepancies between chromosomal, gonadal and phenotypic sex. In congenital hypogonadotropic hypogonadism, a lack of gonadotropin activity results primarily in the absence of pubertal development with prenatal sex development being (almost) unaffected in most patients. To expedite progress in the care of people affected by differences of sex development and congenital hypogonadotropic hypogonadism, the European Union has funded a number of scientific networks. Two Actions of the Cooperation of Science and Technology (COST) programmes - DSDnet (BM1303) and GnRH Network (BM1105) - provided the framework for ground-breaking research and allowed the development of position papers on diagnostic procedures and special laboratory analyses as well as clinical management. Both Actions developed educational programmes to increase expertise and promote interest in this area of science and medicine. In this Perspective article, we discuss the success of the COST Actions DSDnet and GnRH Network and the European Reference Network for Rare Endocrine Conditions (Endo-ERN), and provide recommendations for future research.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Ahmed, Professor Syed Faisal
Authors: Hiort, O., Cools, M., Springer, A., McElreavey, K., Greenfield, A., Wudy, S. A., Kulle, A., Ahmed, S. F., Dessens, A., Balsamo, A., Maghnie, M., Bonomi, M., Dattani, M., Persani, L., and Audi, L.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Nature Reviews Endocrinology
Publisher:Nature Publishing Group
ISSN (Online):1759-5037
Copyright Holders:Copyright © 2019 Springer Nature
First Published:First published in Nature Reviews Endocrinology 15:615-622
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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