Computational time-of-flight diffuse optical tomography

Lyons, A. , Tonolini, F., Boccolini, A., Repetti, A., Henderson, R., Wiaux, Y. and Faccio, D. (2019) Computational time-of-flight diffuse optical tomography. Nature Photonics, 13(8), pp. 575-579. (doi:10.1038/s41566-019-0439-x)

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Abstract

Imaging through a strongly diffusive medium remains an outstanding challenge, in particular in applications in biological and medical imaging. Here, we propose a method based on a single-photon time-of-flight camera that allows, in combination with computational processing of the spatial and full temporal photon distribution data, imaging of an object embedded inside a strongly diffusive medium over more than 80 transport mean free paths. The technique is contactless and requires 1 s acquisition times, thus allowing Hz frame rate imaging. The imaging depth corresponds to several centimetres of human tissue and allows us to perform deep-body imaging as a proof of principle.

Item Type:Articles
Additional Information:D.F. acknowledges financial support from the Engineering and Physical Sciences Research Council (EPSRC, UK, Grant No. EP/M006514/1)
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Faccio, Professor Daniele and Tonolini, Francesco and Lyons, Dr Ashley
Authors: Lyons, A., Tonolini, F., Boccolini, A., Repetti, A., Henderson, R., Wiaux, Y., and Faccio, D.
College/School:College of Science and Engineering > School of Computing Science
College of Science and Engineering > School of Physics and Astronomy
Journal Name:Nature Photonics
Publisher:Nature Research
ISSN:1749-4885
ISSN (Online):1749-4893
Published Online:20 May 2019
Copyright Holders:Copyright © 2019 The Authors
First Published:First published in Nature Photonics 13(8): 575-579
Publisher Policy:Reproduced in accordance with the publisher copyright policy
Data DOI:10.5525/gla.researchdata.642

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
6672319UK Quantum Technology Hub in Enhanced Quantum ImagingMiles PadgettEngineering and Physical Sciences Research Council (EPSRC)EP/M01326X/1S&E P&A - PHYSICS & ASTRONOMY