Multicentre, prospective observational study of the correlation between the Glasgow Admission Prediction Score and adverse outcomes

Jones, D., Cameron, A., Lowe, D. J. , Mason, S. M., O'Keeffe, C. A. and Logan, E. (2019) Multicentre, prospective observational study of the correlation between the Glasgow Admission Prediction Score and adverse outcomes. BMJ Open, 9(8), e026599. (doi: 10.1136/bmjopen-2018-026599) (PMID:31401591) (PMCID:PMC6701614)

Abstract

Objectives: To assess whether the Glasgow Admission Prediction Score (GAPS) is correlated with hospital length of stay, 6-month hospital readmission and 6-month all-cause mortality. This study represents a 6-month follow-up of patients who were included in an external validation of the GAPS’ ability to predict admission at the point of triage. Setting: Sampling was conducted between February and May 2016 at two separate emergency departments (EDs) in Sheffield and Glasgow. Participants: Data were collected prospectively at triage for consecutive adult patients who presented to the ED within sampling times. Any patients who avoided formal triage were excluded from the study. In total, 1420 patients were recruited. Primary outcomes: GAPS was calculated following triage and did not influence patient management. Length of hospital stay, hospital readmission and mortality against GAPS were modelled using survival analysis at 6 months. Results: Of the 1420 patients recruited, 39.6% of these patients were initially admitted to hospital. At 6 months, 30.6% of patients had been readmitted and 5.6% of patients had died. For those admitted at first presentation, the chance of being discharged fell by 4.3% (95% CI 3.2% to 5.3%) per GAPS point increase. Cox regression indicated a 9.2% (95% CI 7.3% to 11.1%) increase in the chance of 6-month hospital readmission per point increase in GAPS. An association between GAPS and 6-month mortality was demonstrated, with a hazard increase of 9.0% (95% CI 6.9% to 11.2%) for every point increase in GAPS. Conclusion: A higher GAPS is associated with increased hospital length of stay, 6-month hospital readmission and 6-month all-cause mortality. While GAPS’s primary application may be to predict admission and support clinical decision making, GAPS may provide valuable insight into inpatient resource allocation and bed planning.

• Item Type: Articles
• Additional Information: Funding: Three of the authors of this paper (DJ, CAOK and SMM) were supported by the NIHR Collaboration for Leadership in Applied Health Research and Care Yorkshire and Humber (NIHR CLAHRC YH). www.clahrc-yh.nihr.ac.uk.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Logan, Dr Eilidh and Cameron, Dr Allan and Lowe, Dr David
• Authors: Jones, D., Cameron, A., Lowe, D. J., Mason, S. M., O'Keeffe, C. A., and Logan, E.
• College/School: College of Medical Veterinary and Life Sciences > School of Life Sciences; College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: BMJ Open
• Publisher: BMJ Publishing Group
• ISSN: 2044-6055
• ISSN (Online): 2044-6055
• Published Online: 10 August 2019
• Copyright Holders: Copyright © 2019 The Author(s) (or their employers)
• First Published: First published in BMJ Open 9(8): e026599
• Publisher Policy: Reproduced under a Creative Commons license