Childs, K. et al. (2019) Suboptimal SVR rates in African patients with atypical Genotype 1 subtypes: implications for global elimination of Hepatitis C. Journal of Hepatology, 71(6), pp. 1099-1105. (doi: 10.1016/j.jhep.2019.07.025) (PMID:31400349)
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Abstract
Direct acting antiviral medications are able to cure Hepatitis C in the majority of patients. The most common genotype of Hepatitis C in Europe and the United States is genotype 1a or 1b and most clinical trials focused on these genotypes. We report that in a group of African patients, most of them had unusual (non-1a/1b) genotype 1 subtypes, and that the cure rate in these unusual genotypes was lower than in genotypes 1a and 1b.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Tong, Dr Lily and Davis, Dr Chris and Da Silva Filipe, Dr Ana and Thomson, Professor Emma |
Authors: | Childs, K., Davis, C., Cannon, M., Montague, S., Filipe, A., Tong, L., Simmonds, P., Smith, D., Thomson, E. C., Dusheiko, G., and Agarwal, K. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research |
Journal Name: | Journal of Hepatology |
Publisher: | Elsevier |
ISSN: | 0168-8278 |
ISSN (Online): | 1600-0641 |
Published Online: | 07 August 2019 |
Copyright Holders: | Copyright © 2019 European Association for the Study of the Liver |
First Published: | First published in Journal of Hepatology 71(6): 1099-1105 |
Publisher Policy: | Reproduced under a Creative Commons License |
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