Morrow, A. , Nordin, S., O'Boyle, P. and Berry, C. (2019) 'Acute micro-coronary syndrome': detailed coronary physiology in a patient with Takotsubo cardiomyopathy. BMJ Case Reports, 12, e229618. (doi: 10.1136/bcr-2019-229618) (PMID:31466973)
|
Text
192568.pdf - Published Version Available under License Creative Commons Attribution. 1MB |
Abstract
Takotsubo cardiomyopathy (TC), otherwise known as stress cardiomyopathy, is characterised by acute, transient left ventricular systolic dysfunction with apical ballooning in the absence of obstructive epicardial coronary stenosis. The presentation of TC mimics that of acute myocardial infarction. More recently there has been a shift towards thinking of TC as a ‘microvascular acute coronary syndrome’. Our case is of an 82-year-old woman who presented with TC mimicking acute anterior ST elevation myocardial infarction in the context of sepsis. Slow flow noted in the left anterior descending artery prompted us to perform coronary physiology. Her fractional flow reserve was 0.91, with an index of myocardial resistance of 117 and a coronary flow reserve of 1.6. In combination these results are indicative of microvascular coronary dysfunction in the absence of significant epicardial stenosis.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Morrow, Dr Andrew and Berry, Professor Colin |
| Authors: | Morrow, A., Nordin, S., O'Boyle, P., and Berry, C. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health |
| Journal Name: | BMJ Case Reports |
| Publisher: | BMJ Publishing Group |
| ISSN: | 1757-790X |
| ISSN (Online): | 1757-790X |
| Published Online: | 28 August 2019 |
| Copyright Holders: | Copyright © BMJ Publishing Group Limited 2019 |
| First Published: | First published in BMJ Case Reports 12:e229618 |
| Publisher Policy: | Reproduced under a Creative Commons license |
University Staff: Request a correction | Enlighten Editors: Update this record
Funder and Project Information
Funder and Project Information