Cleve, S., Inserra, C. and Prentice, P. (2019) Contrast agent microbubble-jetting during initial interaction with 200 kHz focused ultrasound. Ultrasound in Medicine and Biology, 45(11), pp. 3075-3080. (doi: 10.1016/j.ultrasmedbio.2019.08.005) (PMID:31477370)
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191691.pdf - Published Version Available under License Creative Commons Attribution. 1MB |
Abstract
The initial response of microbubbles flowing through a 500-μm polycarbonate capillary to a burst of 200-kHz focused ultrasound, at peak-negative pressure amplitudes from 0.7–1.5 MPa, was investigated with dual-perspective high-speed imaging. Directed jetting through the acoustic focus is demonstrated according to the pressure gradients acting across the cavitating microbubbles. At lower amplitudes, repeated microbubble-jetting is accompanied by sudden, intermittent translation. At higher amplitudes a rebound jet also forms, before disintegration into a cavitation cloud.
| Item Type: | Articles |
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| Additional Information: | The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013)/ERC Grant Agreement No. 336189 (TheraCav), and EPSRC network+ ThUNDDAR (EP/N026942/1) in the UK. SC acknowledges support from LABEX CeLyA (ANR-10-LABX-0060) of Université de Lyon, Investissements d'Avenir (ANR-11-IDEX-0007) program. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Cleve, Sarah and Prentice, Dr Paul |
| Authors: | Cleve, S., Inserra, C., and Prentice, P. |
| College/School: | College of Science and Engineering > School of Engineering > Systems Power and Energy |
| Journal Name: | Ultrasound in Medicine and Biology |
| Publisher: | Elsevier |
| ISSN: | 0301-5629 |
| ISSN (Online): | 1879-291X |
| Published Online: | 29 August 2019 |
| Copyright Holders: | Copyright © 2019 The Authors |
| First Published: | First published in Ultrasound in Medicine and Biology 45(11):3075-3080 |
| Publisher Policy: | Reproduced under a Creative Commons license |
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