Single central nervous system lesions can simulate multiple sclerosis

Grosset, D.G. , Hadley, D.M. and Bone, I. (1989) Single central nervous system lesions can simulate multiple sclerosis. Postgraduate Medical Journal, 65(767), pp. 656-659. (doi: 10.1136/pgmj.65.767.656) (PMID:2608598) (PMCID:PMC2429200)

Full text not currently available from Enlighten.


Three cases are reported in which an initial misdiagnosis of multiple sclerosis was made. In each of these a single central nervous system lesion with space occupying effect was present. These lesions caused confusion because multiple closely running neurological tracts were affected, and there was relapse and remission in the neurological signs and symptoms produced. We conclude that such cases need careful assessment to determine whether a single structural lesion could explain the presentation. Early imaging may show remediable lesions or prevent unnecessary steroid therapy.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Grosset, Dr Donald
Authors: Grosset, D.G., Hadley, D.M., and Bone, I.
College/School:College of Medical Veterinary and Life Sciences > Institute of Neuroscience and Psychology
Journal Name:Postgraduate Medical Journal
Publisher:BMJ Publishing Group
ISSN (Online):1469-0756

University Staff: Request a correction | Enlighten Editors: Update this record