%PDF-1.5
%
56 0 obj
<>
endobj
53 0 obj
<>stream
Acrobat Distiller 7.0 (Windows)
7th January 2016
0-00-00T00:20:16Z
2019-07-23T01:37:56-07:00
Arbortext Advanced Print Publisher 9.1.510/W Unicode
2019-07-23T01:37:56-07:00
application/pdf
NEURIMMINFL2015007468 1..9
uuid:98730f30-6a46-4804-900d-e4c50e02fd01
uuid:c98055b2-1dd1-11b2-0a00-b90098a5ebff
7th January 2016
endstream
endobj
50 0 obj
<>
endobj
52 0 obj
<>
endobj
57 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]/Properties<>/XObject<>>>/Rotate 0/Type/Page>>
endobj
1 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/Type/Page>>
endobj
5 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/Type/Page>>
endobj
8 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB]/XObject<>>>/Rotate 0/Type/Page>>
endobj
12 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB]/XObject<>>>/Rotate 0/Type/Page>>
endobj
16 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB]/XObject<>>>/Rotate 0/Type/Page>>
endobj
20 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Rotate 0/Type/Page>>
endobj
26 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/Type/Page>>
endobj
31 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/Type/Page>>
endobj
120 0 obj
<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Type/Page>>
endobj
130 0 obj
[137 0 R 138 0 R 139 0 R 140 0 R 141 0 R 142 0 R 143 0 R 144 0 R 145 0 R]
endobj
131 0 obj
<>stream
q
367.5943909 0 0 102.3984375 112.7028046 607.6015625 cm
/Im0 Do
Q
BT
/T1_0 1 Tf
12 0 0 12 203.00812 531.99991 Tm
(DOI 10.1212/NXI.0000000000000191)Tj
13.91601 1 Td
(2016;3; )Tj
/T1_1 1 Tf
-15.30604 0 Td
(Neurol Neuroimmunol Neuroinflamm\240)Tj
/T1_0 1 Tf
-2.26298 1.00001 Td
(Faiez Al Nimer, Christina Elliott, Joakim Bergman, et al. )Tj
/T1_2 1 Tf
-6.29351 1 Td
(Lipocalin-2 is increased in progressive multiple sclerosis and inhibits \
remyelination)Tj
ET
BT
/T1_2 1 Tf
12 0 0 12 170.99808 505 Tm
(This information is current as of January 7, 2016)Tj
ET
72 224 449 273 re
0 0 m
S
BT
/T1_2 1 Tf
10 0 0 10 82 467.99997 Tm
(Services)Tj
0 1 TD
(Updated Information &)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 431.0098 467.99997 Tm
( )Tj
0 0 1 rg
-20.00098 0 Td
(http://nn.neurology.org/content/3/1/e191.full.html)Tj
0 g
T*
(including high resolution figures, can be found at:)Tj
ET
BT
/T1_2 1 Tf
10 0 0 10 82 445 Tm
(Supplementary Material)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 487.40002 434.99997 Tm
( )Tj
0 0 1 rg
-25.64 0 Td
(http://nn.neurology.org/content/suppl/2016/01/07/3.1.e191.DC1)Tj
0 g
T*
(Supplementary material can be found at: )Tj
ET
BT
/T1_2 1 Tf
10 0 0 10 82 417 Tm
(References)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 475.99957 406.99997 Tm
( )Tj
0 0 1 rg
-24.49996 0 Td
(http://nn.neurology.org/content/3/1/e191.full.html##ref-list-1)Tj
0 g
T*
(This article cites 40 articles, 11 of which you can access for free at: \
)Tj
ET
BT
/T1_2 1 Tf
10 0 0 10 82 389 Tm
(Subspecialty Collections)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 459.34003 298.99973 Tm
( )Tj
0 0 1 rg
-22.834 0 Td
(http://nn.neurology.org//cgi/collection/multiple_sclerosis)Tj
0 g
/T1_2 1 Tf
T*
(Multiple sclerosis)Tj
/T1_0 1 Tf
23.33197 1.00001 Td
( )Tj
0 0 1 rg
-23.33197 0 Td
(http://nn.neurology.org//cgi/collection/cerebrospinal_fluid)Tj
0 g
/T1_2 1 Tf
T*
(Cerebrospinal Fluid)Tj
/T1_0 1 Tf
24.33301 1 Td
( )Tj
0 0 1 rg
-24.33301 0 Td
(http://nn.neurology.org//cgi/collection/autoimmune_diseases)Tj
0 g
/T1_2 1 Tf
0 1.00001 TD
(Autoimmune diseases)Tj
/T1_0 1 Tf
27.99901 1 Td
( )Tj
0 0 1 rg
-27.99901 0 Td
(http://nn.neurology.org//cgi/collection/all_demyelinating_disease_cns)Tj
0 g
/T1_2 1 Tf
0 1 TD
(All Demyelinating disease \(CNS\))Tj
/T1_0 1 Tf
T*
(following collection\(s\): )Tj
0 1.00001 TD
(This article, along with others on similar topics, appears in the)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 82 270.99997 Tm
(\240 )Tj
/T1_2 1 Tf
0 1 TD
(Permissions & Licensing)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 449.0701 260.99994 Tm
( )Tj
0 0 1 rg
-21.80701 0 Td
(http://nn.neurology.org/misc/about.xhtml#permissions)Tj
0 g
T*
(its entirety can be found online at:)Tj
0 1.00001 TD
(Information about reproducing this article in parts \(figures,tables\) o\
r in)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 82 232.99997 Tm
(\240 )Tj
/T1_2 1 Tf
0 1 TD
(Reprints)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 439.05988 232.99997 Tm
( )Tj
0 0 1 rg
-20.80599 0 Td
(http://nn.neurology.org/misc/addir.xhtml#reprintsus)Tj
0 g
T*
(Information about ordering reprints can be found online:)Tj
ET
72 173 449 46 re
0 0 m
S
BT
/T1_0 1 Tf
10 0 0 10 77 180.99994 Tm
(2016 American Academy of Neurology. All rights reserved. Online ISSN: 23\
32-7812.)Tj
T*
(Published since April 2014, it is an open-access, online-only, continuou\
s publication journal. Copyright \251 )Tj
15.30605 1.00001 Td
(is an official journal of the American Academy of Neurology.)Tj
/T1_1 1 Tf
-15.30605 0 Td
(Neurol Neuroimmunol Neuroinflamm\240)Tj
ET
q
246.75 0 0 77.25 173.125 77.75 cm
-1 TL /Im1 Do
Q
endstream
endobj
135 0 obj
<>/Filter/FlateDecode/Height 256/Length 83633/Name/X/Subtype/Image/Type/XObject/Width 919>>stream
H{PT\.`u13"PLb}<4+˂ڸ2QpР`TRHGvӉ@")Xޞ{{,wQg.=7sAP
yTcL'/!O]ݙa ;FWXUUW[]yrT a2F4{2RVHu0*+*nw+*)Մ
0J2P>Y+/BKdTЏf*{~mf_j]}cC5N /LbUiN8|5L7=L)C?+m)xPyQ2MH+ ؾGsy7Z&CZE*8Vdd]>>>4y-4JD6n#=[opew `0fi^!OP CV`,^nA;w%QCJ/*.5k$f@7ֱ`^xK?K ^frnZZFV)!^2y_Ydd|ưsPMuT#Gϛ;gF'e*uph Bb#kKkCCCͥ'i
8az55S5K{=
˿@paaι>o
Wzp-Eط#CB.
/ v+ן~@!">(9GS:A}@Wf:k2Ml.X*)kJ ;%*\۵;z,;XOqϳckV>jO̬_TqSFھɚL)coL?e=$9dKd( ǁRXa}*!2K>[h
cnu]Z9ZNfN__[
u-vɮ&F KٛVb*|bD58j1fxzNbHv eI\LltVC8"TT?uAb
/} ^,H(WT&ӂTJZ59هsQ2|Ԋw"]:?p2"}<_-tvw6)