Ag2S-Based NIR-emitting Quantum Dots as New Theranostic Materials

Demir Duman, F. , Hocaoglu, I., Gulfem Ozturk, D., Kiraz, A., Gozuacik, D. and Yagci Acar, H. (2014) Ag2S-Based NIR-emitting Quantum Dots as New Theranostic Materials. 2nd International Conference on Bioinspired and Biobased Chemistry and Materials, Nice, France, 15-17 Oct 2014.

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Abstract

Near Infrared (NIR) emitting semiconductor quantum dots (QDs) have attracted great interest as a new class of fluorescent probes for cellular, molecular and in-vivo imaging applications, due to their stable and size-tunable absorption range, large molar extinction coefficient, long luminescence lifetime and higher penetration depth into the tissues than visible light [1, 2]. Recently, Ag2S quantum dots emerged as promising new particles because of the lower cytotoxicity compared to previously reported NIR QDs such as PbS [3], PbSe [4], CdHgTe [5]. Variety of nanoparticles are being designed and tested for gene transfection. QDs provide both a vector basis and a means for optical detection. Therefore, there is a considerable amount of effort in developing QD based gene vectors. In this study, we report the synthesis of Ag2S based theranostic materials, discuss their physical properties and cytotoxicity and demonstrate their superior transfection efficiency.

Item Type:Conference or Workshop Item
Status:Published
Refereed:No
Glasgow Author(s) Enlighten ID:Demir Duman, Dr Fatma
Authors: Demir Duman, F., Hocaoglu, I., Gulfem Ozturk, D., Kiraz, A., Gozuacik, D., and Yagci Acar, H.
Subjects:Q Science > QD Chemistry
College/School:College of Science and Engineering > School of Chemistry

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