Dynamic macromolecular material design-the versatility of cyclodextrin-based host-guest chemistry

Schmidt, B. V.K.J. and Barner-Kowollik, C. (2017) Dynamic macromolecular material design-the versatility of cyclodextrin-based host-guest chemistry. Angewandte Chemie (International Edition), 56(29), pp. 8350-8369. (doi:10.1002/anie.201612150) (PMID:28245083)

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Abstract

Dynamic and adaptive materials are powerful constructs in macromolecular and polymer chemistry with a wide array of applications in drug delivery, bioactive systems, and self‐healing materials. Very often, dynamic materials are based on carefully tailored cyclodextrin host–guest interactions. The precise incorporation of these host and guest moieties into macromolecular building blocks allows the formation of complex macromolecular structures with predefined functions. Thus, dynamic materials with extraordinary adaptive property profiles—responsive to thermal, chemical, and photonic fields—become accessible. This Review explores the hierarchical formation of dynamic materials and complex macromolecular structures from the molecular via the macromolecular to the colloidal and macroscopic level, with a specific emphasis on the functionality and responsiveness of the assemblies, specifically in biological contexts.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Schmidt, Dr Bernhard
Authors: Schmidt, B. V.K.J., and Barner-Kowollik, C.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Angewandte Chemie (International Edition)
Publisher:Wiley
ISSN:1433-7851
ISSN (Online):1521-3773
Published Online:28 February 2017

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