Ghidini, M. and Braconi, C. (2015) Non-coding RNAs in primary liver cancer. Frontiers in Medicine, 2, 36. (doi: 10.3389/fmed.2015.00036) (PMID:26131450) (PMCID:PMC4469108)
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Abstract
Hepatocellular carcinoma (HCC) is a primary malignancy of the liver with poor prognosis and limited therapeutic options. Over the past few years, many studies have evaluated the role of non-coding RNAs (ncRNAs) in hepatocarcinogenesis and tumor progression. ncRNAs were shown to have diagnostic, prognostic, and therapeutic potential in HCC. In this manuscript, we review the latest major discoveries concerning microRNAs and long ncRNAs in HCC pathogenesis, and discuss the potentials and the limitations for their use in clinical practice.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Braconi, Professor Chiara |
| Authors: | Ghidini, M., and Braconi, C. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Frontiers in Medicine |
| Publisher: | Frontiers Media |
| ISSN: | 2296-858X |
| ISSN (Online): | 2296-858X |
| Copyright Holders: | Copyright © 2015 Ghidini and Braconi |
| First Published: | First published in Frontiers in Medicine 2: 36 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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