The changing face of hepatitis B in greater Glasgow: epidemiological trends 1993-2007

Barclay, S.T. et al. (2010) The changing face of hepatitis B in greater Glasgow: epidemiological trends 1993-2007. Scottish Medical Journal, 55(3), pp. 4-7. (doi:10.1258/rsmsmj.55.3.4) (PMID:20795508)

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Background and Aims: Whilst hepatitis B (HBV) is historically uncommon in Scotland, anecdotal experience suggests an increasing prevalence of chronic infection. We sought to establish whether the incidence of chronic HBV is increasing in Greater Glasgow, and whether patients are assessed in secondary care. Methods: The regional virus centre database identified HBV surface antigen (HBsAg) positive samples. For adult patients tested in Glasgow between 1993–2007 the first positive test was identified and classified as acute or chronic infection serologically. Clinic referral and attendance data was then obtained. Results: 1,672 patients tested HBsAg positive; 1051 with chronic infection, 421 acute and 200 indeterminate. New diagnoses of HBV remained stable over time, however falling numbers of acute cases were mirrored by a rise in chronic cases from 40 to 119 per annum between 2000 and 2007. Of 193 patients diagnosed in 2006 and 2007, 51% were not seen in secondary care due to non referral (43%) or non attendance (8%). Conclusion: Chronic HBV trebled in Glasgow between 2000 and 2007. Most patients were not assessed in secondary care. Improved levels of clinic referral and attendance are required to ensure best care for HBV patients in Glasgow.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Stanley, Dr Adrian and Fox, Dr Raymond and Priest, Dr Matthew and Mills, Professor Peter and Forrest, Dr Ewan
Authors: Barclay, S.T., Cameron, S., Mills, P.R., Priest, M., Ross, F., Fox, R., Goulding, C., Forrest, E.H., Morris, A.J., Neilson, M., and Stanley, A.J.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Scottish Medical Journal
Publisher:SAGE Publications
ISSN (Online):2045-6441
Published Online:01 August 2010

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