Cortical functional domains show distinctive oscillatory dynamic in bimanual and mirror visual feedback tasks

Al-Wasity, S. M.H., Pollick, F. , Sosnowska, A. and Vuckovic, A. (2019) Cortical functional domains show distinctive oscillatory dynamic in bimanual and mirror visual feedback tasks. Frontiers in Computational Neuroscience, 13, 30. (doi:10.3389/fncom.2019.00030)

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Abstract

It is believed that Mirror Visual Feedback (MVF) increases the interlimb transfer but the exact mechanism is still a matter of debate. The aim of this study was to compare between a bimanual task (BM) and a MVF task, within functionally rather than geometrically defined cortical domains. Measure Projection Analysis (MPA) approach was applied to compare the dynamic oscillatory activity (event-related synchronization/desynchronization ERS/ERD) between and within domains. EEG was recorded in 14 healthy participants performing a BM and an MVF task with the right hand. The MPA was applied on fitted equivalent current dipoles based on independent components to define domains containing functionally similar areas. The measure of intradomain similarity was a “signed mutual information,” a parameter based on the coherence. Domain analysis was performed for joint tasks (BM and MVF) and for each task separately. MVF created 9 functional domains while MB task had only 4 functionally distinctive domains, two over the left hemispheres and two bilateraly. For all domains identified for BM task alone, similar domains could be identified in MVF and joint tasks analysis. In addition MVF had domains related to motor planning on the right hemisphere and to self-recognition of action. For joint tasks analysis, seven domains were identified, with similar functions for the left and the right hand with exception of a domain covering BA32 (self-recognition of action) of the left hand only. In joint task domain analysis, the ERD/ERS showed a larger difference between domains than between tasks. All domains which involved the sensory cortex had a visible beta ERS at the onset of movement, and post movement beta ERS. The frequency of ERD varied between domains. Largest difference between tasks existed in domains responsible for the awareness of action. In conclusion, functionally distinctive domains have different ERD/ERS patterns, similar for both tasks. MVF activates contralateral hemisphere in similar manner to BM movements, while at the same time also activating the ipsilateral hemisphere. Significance: Following stroke cortical activation and interhemispheric inhibition from the contralesional side is reduced. MVF creates stronger ipsilateral activity than BM, which is highly relevant of neurorehabilitation of movements.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Sosnowska, Anna and Pollick, Professor Frank and Al-Wasity, Mr Salim and Vuckovic, Dr Aleksandra
Authors: Al-Wasity, S. M.H., Pollick, F., Sosnowska, A., and Vuckovic, A.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
College of Science and Engineering > School of Engineering > Biomedical Engineering
College of Science and Engineering > School of Psychology
Journal Name:Frontiers in Computational Neuroscience
Publisher:Frontiers Media
ISSN:1662-5188
ISSN (Online):1662-5188
Copyright Holders:Copyright © 2019 Al-Wasity, Pollick, Sosnowska and Vuckovic
First Published:First published in Frontiers in Computational Neuroscience 13: 30
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
701101EPSRC 2015 DTPMary Beth KneafseyEngineering and Physical Sciences Research Council (EPSRC)EP/M508056/1R&I - RESEARCH STRATEGY & INNOVATION