Cross-frequency synchronization connects networks of fast and slow oscillations during visual working memory maintenance

Siebenhühner, F., Wang, S. H., Palva, J. M. and Palva, S. (2016) Cross-frequency synchronization connects networks of fast and slow oscillations during visual working memory maintenance. eLife, 5, e13451. (doi:10.7554/eLife.13451) (PMID:27669146) (PMCID:PMC5070951)

Siebenhühner, F., Wang, S. H., Palva, J. M. and Palva, S. (2016) Cross-frequency synchronization connects networks of fast and slow oscillations during visual working memory maintenance. eLife, 5, e13451. (doi:10.7554/eLife.13451) (PMID:27669146) (PMCID:PMC5070951)

[img]
Preview
Text
179538.pdf - Published Version
Available under License Creative Commons Attribution.

4MB

Abstract

Neuronal activity in sensory and fronto-parietal (FP) areas underlies the representation and attentional control, respectively, of sensory information maintained in visual working memory (VWM). Within these regions, beta/gamma phase-synchronization supports the integration of sensory functions, while synchronization in theta/alpha bands supports the regulation of attentional functions. A key challenge is to understand which mechanisms integrate neuronal processing across these distinct frequencies and thereby the sensory and attentional functions. We investigated whether such integration could be achieved by cross-frequency phase synchrony (CFS). Using concurrent magneto- and electroencephalography, we found that CFS was load-dependently enhanced between theta and alpha–gamma and between alpha and beta-gamma oscillations during VWM maintenance among visual, FP, and dorsal attention (DA) systems. CFS also connected the hubs of within-frequency-synchronized networks and its strength predicted individual VWM capacity. We propose that CFS integrates processing among synchronized neuronal networks from theta to gamma frequencies to link sensory and attentional functions.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Palva, Professor Matias and Palva, Professor Satu
Authors: Siebenhühner, F., Wang, S. H., Palva, J. M., and Palva, S.
College/School:College of Medical Veterinary and Life Sciences > Institute of Neuroscience and Psychology
Journal Name:eLife
Publisher:eLife Sciences Publications
ISSN:2050-084X
ISSN (Online):2050-084X
Copyright Holders:Copyright © 2016 Siebenhuhner et al.
First Published:First published in eLife 5:e13451
Publisher Policy:Reproduced under a Creative Commons License

University Staff: Request a correction | Enlighten Editors: Update this record