Mangion, K., Burke, N. M.M., Mccomb, C., Carrick, D., Woodward, R. and Berry, C. (2019) Feature-tracking myocardial strain in healthy adults- a magnetic resonance study at 3.0 tesla. Scientific Reports, 9, 3239. (doi: 10.1038/s41598-019-39807-w) (PMID:30824793) (PMCID:PMC6397185)
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Abstract
We analyzed feature-tracking derived circumferential and longitudinal strain in healthy volunteers who underwent cardiac magnetic resonance imaging (CMR) at 3.0 T. 88 healthy adults (44.6 ± 18.0 years old, 49% male), without prior cardiovascular disease, underwent CMR at 3.0 T including cine, and late gadolinium enhancement in subjects >45 years. LV functional analysis and feature-tracking strain analyses were carried out. Global strain had better reproducibility than segmental strain. There was a sex specific difference global longitudinal strain (mean ± SD, −18.48 ± 3.65% (male), −21.91 ± 3.01% (female), p < 0.001), but not global circumferential strain (mean ± SD, −25.41 ± 4.50% (male), −27.94 ± 3.48% (female), p = 0.643). There was no association of strain with ageing after accounting for sex for both global longitudinal and circumferential strain. Feature-tracking strain analysis is feasible at 3.0 T. Healthy female volunteers demonstrated higher magnitudes of global longitudinal strain when compared to male counterparts. Whilst global cine-strain has good reproducibility, segmental strain does not.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Mccomb, Dr Christie and Carrick, Dr David and Mangion, Dr Kenneth and Woodward, Miss Rosemary and Burke, Dr Nicole and Berry, Professor Colin |
| Authors: | Mangion, K., Burke, N. M.M., Mccomb, C., Carrick, D., Woodward, R., and Berry, C. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
| Journal Name: | Scientific Reports |
| Publisher: | Nature Research |
| ISSN: | 2045-2322 |
| ISSN (Online): | 2045-2322 |
| Copyright Holders: | Copyright © 2019 The Authors |
| First Published: | First published in Scientific Reports 9: 3239 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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