Drug resistance in protozoan parasites

de Koning, H. P. (2017) Drug resistance in protozoan parasites. Emerging Topics in Life Sciences, 1(6), pp. 627-632. (doi: 10.1042/ETLS20170113)

Abstract

As with all other anti-infectives (antibiotics, anti-viral drugs, and anthelminthics), the limited arsenal of anti-protozoal drugs is being depleted by a combination of two factors: increasing drug resistance and the failure to replace old and often shamefully inadequate drugs, including those compromised by (cross)-resistance, through the development of new anti-parasitics. Both factors are equally to blame: a leaking bathtub may have plenty of water if the tap is left open; if not, it will soon be empty. Here, I will reflect on the factors that contribute to the drug resistance emergency that is unfolding around us, specifically resistance in protozoan parasites.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: De Koning, Professor Harry
• Authors: de Koning, H. P.
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity
• Journal Name: Emerging Topics in Life Sciences
• Publisher: Portland Press
• ISSN: 2397-8554
• ISSN (Online): 2397-8562
• Copyright Holders: Copyright © 2017 The Author
• First Published: First published in Emerging Topics in Life Sciences 1(6): 627-632
• Publisher Policy: Reproduced under a Creative Commons License