Investigating the breakdown of the nerve agent simulant methyl paraoxon and chemical warfare agents GB and VX using nitrogen containing bases

Wilson, C., Cooper, N. J., Briggs, M. E., Cooper, A. I. and Adams, D. J. (2018) Investigating the breakdown of the nerve agent simulant methyl paraoxon and chemical warfare agents GB and VX using nitrogen containing bases. Organic and Biomolecular Chemistry, 16(47), pp. 9285-9291. (doi:10.1039/C8OB02475H) (PMID:30480295)

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Abstract

A range of nitrogen containing bases was tested for the hydrolysis of a nerve agent simulant, methyl paraoxon (MP), and the chemical warfare agents, GB and VX. The product distribution was found to be highly dependant on the basicity of the base and the quantity of water used for the hydrolysis. This study is important in the design of decontamination technology, which often involve mimics of CWAs.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Adams, Dave
Authors: Wilson, C., Cooper, N. J., Briggs, M. E., Cooper, A. I., and Adams, D. J.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Organic and Biomolecular Chemistry
Publisher:Royal Society of Chemistry
ISSN:1477-0520
ISSN (Online):1477-0539
Published Online:21 November 2018
Copyright Holders:Copyright © 2018 The Royal Society of Chemistry
First Published:First published in Organic and Biomolecular Chemistry 16(47): 9285-9291
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
768041Multicomponent Supramolecular HydrogelsDave AdamsEngineering and Physical Sciences Research Council (EPSRC)EP/L021978/2SCHOOL OF CHEMISTRY