Who benefits from a defibrillator—balancing the risk of sudden versus non-sudden death

Beggs, S. A.S. , Gardner, R. S. and McMurray, J. J.V. (2018) Who benefits from a defibrillator—balancing the risk of sudden versus non-sudden death. Current Heart Failure Reports, 15(6), pp. 376-389. (doi:10.1007/s11897-018-0416-6) (PMID:30413991) (PMCID:PMC6267371)

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Abstract

Purpose of Review: Treatment with a defibrillator can reduce the risk of sudden death by terminating ventricular arrhythmias. The identification of patient groups in whom this function reduces overall mortality is challenging. In this review, we summarise the evidence for who benefits from a defibrillator. Recent Findings: Recent evidence suggests that contemporary pharmacologic and non-defibrillator device therapies are altering the potential risks and benefits of a defibrillator. Summary: Who benefits from a defibrillator is determined by both the risk of sudden death and the competing risk of other, non-sudden causes of death. The balance of these risks is changing, which calls into question whether historic evidence for the use of defibrillators remains robust in the modern era.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Gardner, Professor Roy and Beggs, Dr Simon and McMurray, Professor John
Authors: Beggs, S. A.S., Gardner, R. S., and McMurray, J. J.V.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Current Heart Failure Reports
Publisher:Springer
ISSN:1546-9530
ISSN (Online):1546-9549
Published Online:10 November 2018
Copyright Holders:Copyright © 2018 The Authors
First Published:First published in Current Heart Failure Reports 15(6): 376-389
Publisher Policy:Reproduced under a Creative Commons License

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