Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours?

Clark, M. E. et al. (2019) Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours? Journal of Public Health, 41(3), pp. 600-608. (doi: 10.1093/pubmed/fdy158) (PMID:30272192)

Abstract

Background: Lung cancer screening can reduce lung cancer mortality by 20%. Screen-detected abnormalities may provide teachable moments for smoking cessation. This study assesses impact of pulmonary nodule detection on smoking behaviours within the first UK trial of a novel auto-antibody test, followed by chest x-ray and serial CT scanning for early detection of lung cancer (Early Cancer Detection Test–Lung Cancer Scotland Study). Methods: Test-positive participants completed questionnaires on smoking behaviours at baseline, 1, 3 and 6 months. Logistic regression compared outcomes between nodule (n = 95) and normal CT groups (n = 174) at 3 and 6 months follow-up. Results: No significant differences were found between the nodule and normal CT groups for any smoking behaviours and odds ratios comparing the nodule and normal CT groups did not vary significantly between 3 and 6 months. There was some evidence the nodule group were more likely to report significant others wanted them to stop smoking than the normal CT group (OR across 3- and 6-month time points: 3.04, 95% CI: 0.95, 9.73; P = 0.06). Conclusion: Pulmonary nodule detection during lung cancer screening has little impact on smoking behaviours. Further work should explore whether lung cancer screening can impact on perceived social pressure and promote smoking cessation.

• Item Type: Articles
• Additional Information: This work was supported by a National Institute for Health Research School for Primary Care Research funded academic clinical fellowship. The Early Cancer Detection Test–Lung Cancer Scotland Study study was supported by the Chief Scientist Office and Oncimmune Ltd. The follow-up data collection was supported by University of Nottingham PhD studentships and by Oncimmune Ltd.
• Keywords: Public health, environmental and occupational health, general medicine.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Young, Dr Ben and Mair, Professor Frances
• Authors: Clark, M. E., Young, B., Bedford, L. E., das Nair, R., Robertson, J. F.R., Vedhara, K., Sullivan, F., Mair, F. S., Schembri, S., Littleford, R. C., and Kendrick, D.
• College/School: College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > General Practice and Primary Care; College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Mental Health and Wellbeing
• Journal Name: Journal of Public Health
• Publisher: Oxford University Press
• ISSN: 1741-3842
• ISSN (Online): 1741-3850
• Published Online: 29 September 2018
• Copyright Holders: Copyright © 2018 The Authors
• First Published: First published in Journal of Public Health 41:600-608
• Publisher Policy: Reproduced in accordance with the publisher copyright policy