Impact of deprivation on cardiovascular risk factors in people with diabetes: an observational study

Wild, S., Macleod, F., McKnight, J., Watt, G., Mackenzie, C., Ford, I. , McConnachie, A. and Lindsay, R. (2008) Impact of deprivation on cardiovascular risk factors in people with diabetes: an observational study. Diabetic Medicine, 25(2), pp. 194-199. (doi: 10.1111/j.1464-5491.2008.02382.x)

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Abstract

AIM To examine the influence of deprivation on prevalence of diabetes and of cardiovascular disease risk factors in people with diabetes. METHODS Cross-sectional study of 52 280 people in diabetes registers of Greater Glasgow and Lothian NHS Board areas linked to hospital admission data. RESULTS Age- and sex-adjusted prevalence of diabetes increased from 2.3% in the least deprived quintile (Q1) to 3.3% in the most deprived quintile (Q5; P < 0.001), as did prevalence of vascular disease (Q1 20%, Q5 27%; P < 0.001). Prevalence of current smoking (Q1 13%, Q5 32%; P < 0.001), obesity (Q1 38%, Q5 51%; P < 0.001) and above-target glycated haemoglobin (HbA1c; = 7.5%: Q1 46% vs. Q5 47%; P = 0.01) were higher in the most deprived quintile. In contrast, the proportion of people with above-target cholesterol were similar (proportion = 5.0 mmol/l: Q1 26%, Q5 24%; P = 0.07) and the proportion of people with above-target systolic blood pressure (SBP) was lower (SBP = 140 mmHg: Q1 44%, Q5 37%; P = 0.02) in the most deprived quintile. In people with diabetes and prevalent vascular disease, deprivation was associated with failure to reach cholesterol target [odds ratio cholesterol = 5.0 mmol/l: Q5 vs. Q1 1.23 (1.04–1.45) P = 0.013]. SBP and cholesterol were markedly lower compared with previous population surveys. CONCLUSIONS The burden of diabetes and vascular disease is greater in more deprived populations. Our data confirm a major advance in management of cholesterol and blood pressure management. Deprivation is still associated with failure to reach cholesterol targets in secondary prevention as well as higher prevalence of obesity and smoking.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Lindsay, Dr Robert and McConnachie, Professor Alex and McKnight, Dr Janice and Ford, Professor Ian and Watt, Professor Graham
Authors: Wild, S., Macleod, F., McKnight, J., Watt, G., Mackenzie, C., Ford, I., McConnachie, A., and Lindsay, R.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Robertson Centre
College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > General Practice and Primary Care
College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Clinical Specialities
Journal Name:Diabetic Medicine
Publisher:Blackwell Publishing
ISSN:0742-3071

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