Patient-specific modeling of heart valves: From image to simulation

Aggarwal, A. , Aguilar, V. S., Lee, C.-H., Ferrari, G., Gorman, J. H., Gorman, R. C. and Sacks, M. S. (2013) Patient-specific modeling of heart valves: From image to simulation. In: Ourselin, S., Rueckert, D. and Smith, N. (eds.) Functional Imaging and Modeling of the Heart. Series: Lecture notes in computer science (7945). Springer, pp. 141-149. ISBN 9783642388989 (doi: 10.1007/978-3-642-38899-6_17)

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Abstract

Heart valves play a very important role in the functioning of the heart and many of the heart failures are related to the valvular dysfunctions, e.g. aortic stenosis and mitral regurgitation. As the medical field is moving towards a patient-specific diagnosis and treatment procedures, modeling of heart valves with patient-specific information is becoming a significant tool in medical field. Here we present the ingredients for valve simulation specifically the aortic valve, with a main focus on a novel spline-based mapping technique which solves many issues in generating patient-specific models – the microstructural mapping, the pre-strain calculations, prescribing dynamic boundary conditions, validation and inverse-modeling to obtain material parameters.

Item Type:Book Sections
Additional Information:Online ISBN: 9783642388996.
Status:Published
Glasgow Author(s) Enlighten ID:Aggarwal, Dr Ankush
Authors: Aggarwal, A., Aguilar, V. S., Lee, C.-H., Ferrari, G., Gorman, J. H., Gorman, R. C., and Sacks, M. S.
College/School:College of Science and Engineering > School of Engineering > Infrastructure and Environment
Publisher:Springer
ISSN:0302-9743
ISBN:9783642388989

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