Mouse models of abnormal skeletal development and homeostasis

McLean, W. and Olsen, B. R. (2001) Mouse models of abnormal skeletal development and homeostasis. Trends in Genetics, 17(10), S38-S43. (doi: 10.1016/S0168-9525(01)02458-1) (PMID:11585675)

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Abstract

Studies of a number of mouse mutations with skeletal defects have contributed significantly to the understanding of bone development and homeostasis. In many cases, such mutants are also genetic models of disorders in humans, characterized by reduced bone mass (osteoporosis), increased bone mass (osteopetrosis), or abnormalities in endochondral ossification (chondrodysplasias).

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Mclean, Professor William
Authors: McLean, W., and Olsen, B. R.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School
Journal Name:Trends in Genetics
Publisher:Elsevier (Cell Press)
ISSN:0168-9525
ISSN (Online):1362-4555

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