A Multi Modal Clearing Method for Brain Imaging

Costantini, I., Allegra Mascaro, A. L., Di Giovanna, A. P., Silvestri, L., Müllenbroich, M. C. , Sacconi, L. and Pavone, F. S. (2015) A Multi Modal Clearing Method for Brain Imaging. Optics and the Brain 2015, Vancouver, Canada, 12-15 Apr 2015. BrM3B.2. ISBN 9781557529541 (doi:10.1364/boda.2015.brm3b.2)

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Abstract

In this work we investigate the effectiveness of a water-soluble agent, the 2,2′-thiodiethanol (TDE) to clear mouse and human brain. TDE is suitable with two-photon fluorescence microscopy and in combination with CLARITY with light sheet microscopy.

Item Type:Conference or Workshop Item
Additional Information:Optics in the Life Sciences OSA Technical Digest (online) (Optical Society of America, 2015), paper BrM3B.2
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Muellenbroich, Dr Caroline
Authors: Costantini, I., Allegra Mascaro, A. L., Di Giovanna, A. P., Silvestri, L., Müllenbroich, M. C., Sacconi, L., and Pavone, F. S.
College/School:College of Science and Engineering > School of Physics and Astronomy
ISBN:9781557529541

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