Gherman, S. and Philiastides, M. G. (2018) Human VMPFC encodes early signatures of confidence in perceptual decisions. eLife, 7, e38293. (doi: 10.7554/eLife.38293.001) (PMID:30247123) (PMCID:PMC6199131)
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Abstract
Choice confidence, an individual’s internal estimate of judgment accuracy, plays a critical role in adaptive behaviour, yet its neural representations during decision formation remain underexplored. Here, we recorded simultaneous EEG-fMRI while participants performed a direction discrimination task and rated their confidence on each trial. Using multivariate single-trial discriminant analysis of the EEG, we identified a stimulus-independent component encoding confidence, which appeared prior to subjects’ explicit choice and confidence report, and was consistent with a confidence measure predicted by an accumulation-to-bound model of decisionmaking. Importantly, trial-to-trial variability in this electrophysiologically-derived confidence signal was uniquely associated with fMRI responses in the ventromedial prefrontal cortex (VMPFC), a region not typically associated with confidence for perceptual decisions. Furthermore, activity in the VMPFC was functionally coupled with regions of the frontal cortex linked to perceptual decision-making and metacognition. Our results suggest that the VMPFC holds an early confidence representation arising from decision dynamics, preceding and potentially informing metacognitive evaluation.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Gherman, Miss Sabina and Philiastides, Professor Marios |
Creator Roles: | Gherman, S.Conceptualization, Resources, Data curation, Software, Formal analysis, Validation, Investigation, Visualization, Methodology, Writing – original draft, Writing – review and editing Philiastides, M. G.Conceptualization, Resources, Software, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Methodology, Writing – original draft, Project administration, Writing – review and editing |
Authors: | Gherman, S., and Philiastides, M. G. |
College/School: | College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience |
Journal Name: | eLife |
Publisher: | eLife Sciences Publications |
ISSN: | 2050-084X |
ISSN (Online): | 2050-084X |
Copyright Holders: | Copyright © 2018 Gherman and Philiastides |
First Published: | First published in eLife 7: e38293 |
Publisher Policy: | Reproduced under a Creative Commons License |
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