Walking pace is associated with lower risk of all-cause and cause-specific mortality

Celis-Morales, C. A. et al. (2018) Walking pace is associated with lower risk of all-cause and cause-specific mortality. Medicine and Science in Sports and Exercise, (doi:10.1249/MSS.0000000000001795) (PMID:30303933) (Early Online Publication)

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Abstract

Purpose: Walking pace is associated with all-cause and cardiovascular disease (CVD) mortality. Whether this association extends to other health outcomes and whether it is independent of total amount of time walked are currently unknown. Therefore, the aim of this study was to investigate whether usual walking pace is associated with a range of health outcomes. Methods: 318,185 UK Biobank participants (54% women) aged 40-69 years were included. Walking pace and total walking time were self-reported. The outcomes comprised: all-cause mortality as well as incidence and mortality from cardiovascular disease (CVD), respiratory disease and cancer. The associations were investigated using Cox proportional hazard models. Results: Over a mean of 5.0 years [ranging from 3.3 to 7.8], 5,890 participants died, 18,568 developed CVD, 5,430 respiratory disease and 19,234 cancer. In a fully adjusted model, compared to slow pace walkers, men and women, respectively, with a brisk pace having lower risk of mortality from all-causes (HR0.79 [95% CI: 0.69; 0.90] and 0.73 [95% CI: 0.62; 0.85]), CVD (HR 0.62 [0.50; 0.76] and 0.80 [0.73; 0.88]), respiratory disease (HR 0.58 [95% CI 0.43; 0.78] and 0.66 [0.57; 0.77]), COPD (HR 0.26 [95% 0.12; 0.56] and 0.28 [0.16; 0.49]). No associations were found for all-cause cancer, colorectal, breast cancer. However, brisk walking was associated with a higher risk of prostate cancer. Conclusions: Walking pace is associated with lower risk of a wide range of important health conditions, independently of overall time spent walking.

Item Type:Articles
Status:Early Online Publication
Refereed:Yes
Glasgow Author(s) Enlighten ID:Celis, Dr Carlos and Gray, Dr Stuart and Gill, Professor Jason and Welsh, Dr Paul and Anderson, Dr Jana and Iliodromiti, Dr Stamatina and Pell, Professor Jill and Petermann, Mrs Fanny and Sattar, Professor Naveed and Pellicori, Dr Pierpaolo and Lyall, Dr Donald
Authors: Celis-Morales, C. A., Gray, S., Petermann, F., Iliodromiti, S., Welsh, P., Lyall, D. M., Anderson, J., Pellicori, P., Mackay, D. F., Pell, J. P., Sattar, N., and Gill, J. M.R.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Public Health
College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Robertson Centre
Journal Name:Medicine and Science in Sports and Exercise
Publisher:American College of Sports Medicine
ISSN:0195-9131
ISSN (Online):1530-0315
Published Online:09 October 2018

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