Gamba-Sanchez, D. and Prunet, J. (2018) Synthesis of 1,3-diols by O-nucleophile additions to activated alkenes. Synthesis, 50(20), pp. 3997-4007. (doi: 10.1055/s-0037-1610248)
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Abstract
The diastereoselective synthesis of 1,3-diols by addition of oxygen nucleophiles to activated alkenes is presented. This review focuses on homoallylic alcohol substrates that react with a relay compound to form an intermediate oxygen nucleophile, which in turn will lead to a protected 1,3-diol by intramolecular addition to the olefin moiety.
Item Type: | Articles |
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Additional Information: | Financial support was provided by Fondo de Investigaciones de la Facultad de Ciencias de la Universidad de los Andes, convocatoria 2018-2019 para la Financiación de Programas de Investigación “use of threonine as chiral auxiliary” |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Prunet, Dr Joelle |
Authors: | Gamba-Sanchez, D., and Prunet, J. |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Synthesis |
Publisher: | Georg Thieme Verlag |
ISSN: | 0039-7881 |
ISSN (Online): | 1437-210X |
Published Online: | 30 August 2018 |
Copyright Holders: | Copyright © 2018 Georg Thieme Verlag |
First Published: | First published in Synthesis 50(20): 3997-4007 |
Publisher Policy: | Reproduced in accordance with the publisher copyright policy |
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