Macrae, V.E., Wong, S.C. , Farquharson, C. and Ahmed, S.F. (2006) Cytokine actions in growth disorders associated with pediatric chronic inflammatory diseases (Review). International Journal of Molecular Medicine, 18(6), pp. 1011-1018. (doi: 10.3892/ijmm.18.6.1011) (PMID:17089003)
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Abstract
Growth disorders are commonly observed in children suffering from chronic inflammatory diseases such as Juvenile Idiopathic Arthritis (JIA) and Inflammatory Bowel Disease (IBD). These disorders range from general growth retardation to local acceleration of growth in the affected limb and are associated with the increased production of pro-inflammatory cytokines. In this article, we review how cytokines influence child growth by exerting a local effect at the level of the growth plate, and through systemic effects throughout the whole body.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Wong, Dr Jarod and Ahmed, Professor Syed Faisal |
| Authors: | Macrae, V.E., Wong, S.C., Farquharson, C., and Ahmed, S.F. |
| College/School: | College of Medical Veterinary and Life Sciences |
| Journal Name: | International Journal of Molecular Medicine |
| Journal Abbr.: | Int J Mol Med |
| Publisher: | Spandidos Publications |
| ISSN: | 1107-3756 |
| ISSN (Online): | 1791-244X |
| Published Online: | 01 December 2006 |
| Published Online: | 01 December 2006 |
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