Dunne, K. A. , Hill, J. and Dillon, J.F. (2006) Treatment of chronic transfusion-dependent gastric antral vascular ectasia (watermelon stomach) with thalidomide. European Journal of Gastroenterology and Hepatology, 18(4), pp. 455-456. (doi: 10.1097/00042737-200604000-00024) (PMID:16538122)
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Abstract
Gastric antral vascular ectasia (GAVE; watermelon stomach) is a rare but increasingly recognized cause of chronic gastrointestinal blood loss and iron deficiency anaemia and, rarely, life-threatening haemorrhage. Treatment modalities include endoscopic, pharmacological and surgical approaches; however, many patients remain transfusion dependent. Thalidomide has previously been shown to exert a potent antiangiogenic effect in experimental studies [1], its therapeutic role in gastrointestinal bleeding associated with vascular ectasia and angiodysplasia, however, remains unclear. We successfully treated a patient with refractory anaemia secondary to GAVE with thalidomide.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Puxty, Dr Kathryn |
Authors: | Dunne, K. A., Hill, J., and Dillon, J.F. |
College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
Journal Name: | European Journal of Gastroenterology and Hepatology |
Publisher: | Lippincott, Williams & Wilkins |
ISSN: | 0954-691X |
ISSN (Online): | 1473-5687 |
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