Disability among Ebola survivors and their close contacts in Sierra Leone: a retrospective case-controlled cohort study

Jagadesh, S., Sevalie, S., Fatoma, R., Sesay, F., Sahr, F., Faragher, B., Semple, M. G., Fletcher, T. E., Weigel, R. and Scott, J. T. (2018) Disability among Ebola survivors and their close contacts in Sierra Leone: a retrospective case-controlled cohort study. Clinical Infectious Diseases, 66(1), pp. 131-133. (doi: 10.1093/cid/cix705) (PMID:29020205) (PMCID:PMC5833946)

Abstract

Ebola survivors (21/27 [77.8%]) suffered more disability than their close contacts (6/54 [11.1%]) (adjusted odds ratio, 23.5 [95% confidence interval, 6.5-85.7]; P < .001) when measured by the Washington Group Disability Extended Questionnaire. Major limitations in vision, mobility, cognition, and affect were observed in survivors 1 year following the 2014-2016 Ebola outbreak, highlighting the need for long-term rehabilitation.

• Item Type: Articles
• Additional Information: The study was part of a Master’s dissertation for the Liverpool School of Tropical Medicine and was facilitated by a wider project, “Characterising Post Ebola Syndrome, Sierra Leone” supported by the Wellcome Trust Enhancing Research Activity in Epidemic Situations (ERAES program [grants to J. T. S. and M. G. S.]). J. T. S. and M. G. S. are supported by the UK National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections. T. F. is funded by the Wellcome Trust (104480/Z/14/Z) and the UK Ministry of Defence.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Scott, Dr Janet
• Authors: Jagadesh, S., Sevalie, S., Fatoma, R., Sesay, F., Sahr, F., Faragher, B., Semple, M. G., Fletcher, T. E., Weigel, R., and Scott, J. T.
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity; College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
• Journal Name: Clinical Infectious Diseases
• Publisher: Oxford University Press
• ISSN: 1058-4838
• ISSN (Online): 1537-6591
• Published Online: 20 August 2017
• Copyright Holders: Copyright © 2017 The Authors
• First Published: First published in Clinical Infectious Diseases 66(1): 131-133
• Publisher Policy: Reproduced under a Creative Commons License