Connell, J, and Mclaren, E.H. (1981) Partial end organ resistance to thyroid-hormone in congenital hypothyroidism. Postgraduate Medical Journal, 57 (670). pp. 518-520. ISSN 0032-5473 (doi:10.1136/pgmj.57.670.518 )
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Publisher's URL: http://dx.doi.org/10.1136/pgmj.57.670.518
End organ resistance to thyroid hormone has been described for a number of years: the defect may be partial or generalized. A case of partial end organ resistance to thyroid hormone in congenital hypothyroidism is described, with evidence of an alteration in TSH threshold to feedback inhibition by thyroid hormone. The implications of this factor in the management of hypothyroidism are discussed.
|Glasgow Author(s):||Connell, Prof John|
|Authors:||Connell, J, and Mclaren, E.H.|
|Subjects:||R Medicine > R Medicine (General)|
|College/School:||College of Medical Veterinary and Life Sciences|
|Journal Name:||Postgraduate Medical Journal|
|Journal Abbr.:||Postgrad. med. j.|