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Partial end organ resistance to thyroid-hormone in congenital hypothyroidism

Connell, J, and Mclaren, E.H. (1981) Partial end organ resistance to thyroid-hormone in congenital hypothyroidism. Postgraduate Medical Journal, 57 (670). pp. 518-520. ISSN 0032-5473 (doi:10.1136/pgmj.57.670.518 )

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Publisher's URL: http://dx.doi.org/10.1136/pgmj.57.670.518

Abstract

End organ resistance to thyroid hormone has been described for a number of years: the defect may be partial or generalized. A case of partial end organ resistance to thyroid hormone in congenital hypothyroidism is described, with evidence of an alteration in TSH threshold to feedback inhibition by thyroid hormone. The implications of this factor in the management of hypothyroidism are discussed.

Item Type:Article
Status:Published
Refereed:Yes
Glasgow Author(s):Connell, Prof John
Authors: Connell, J, and Mclaren, E.H.
Subjects:R Medicine > R Medicine (General)
College/School:College of Medical Veterinary and Life Sciences
Journal Name:Postgraduate Medical Journal
Journal Abbr.:Postgrad. med. j.
ISSN:0032-5473
ISSN (Online):1469-0756

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