Magnetoresistive biosensors for on-chip detection and localisation of paramagnetic particles

Yin, Z., Bonizzoni, E. and Heidari, H. (2018) Magnetoresistive biosensors for on-chip detection and localisation of paramagnetic particles. IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology, 2(3), pp. 179-185. (doi:10.1109/JERM.2018.2858562)

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Abstract

This paper presents the design and the implementation of an on-chip magnetoresistive sensors array for cell detection and localisation. Giant magnetoresistance (GMR) sensors have been used due to their high sensitivity and resolution. A new calibration and localisation algorithm has been coded and implemented. In order to generate the required homogenous magnetic field, a custom 3D printed Hallbach cylinder has been simulated and characterised. The system includes sensory and electronic boards to collect the data and to transfer them to a computing server. The experimental results are displayed in a visual interface. Ferrofluid is used to model and simulate the magnetic field change of the cell. This paper demonstrates a 4×4 sensors array and provides a step towards the miniaturised on-chip magnetoresistive based cell detection and localisation for portable diagnostics applications.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Heidari, Dr Hadi
Authors: Yin, Z., Bonizzoni, E., and Heidari, H.
College/School:College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
Journal Name:IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology
Publisher:IEEE
ISSN:2469-7257
ISSN (Online):2469-7257
Published Online:23 July 2018
Copyright Holders:Copyright © 2018 IEEE
First Published:First published in IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology 2(3):179-185
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
3028770Magnetic Diagnostics Setup for Lab-on-Chip ApplicationHadi HeidariThe Royal Society (ROYSOC)RSG\R1|180269ENG - Electronics & Nanoscale Engineering