Diabetes, left ventricular systolic dysfunction, and chronic heart failure

MacDonald, M.R., Petrie, M.C., Hawkins, N.M., Petrie, J.R. , Fisher, M., McKelvie, R., Aguilar, D., Krum, H. and McMurray, J.J.V. (2008) Diabetes, left ventricular systolic dysfunction, and chronic heart failure. European Heart Journal, 29(10), pp. 1224-1240. (doi:10.1093/eurheartj/ehn156)

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Abstract

Chronic heart failure (HF) and diabetes mellitus (DM) commonly coexist. Each condition increases the likelihood of developing the other, and when they occur together in the same patient the risk of morbidity and mortality increases markedly. We discuss the epidemiological overlap and consider the complex patho-physiological pathways linking the two diseases. The treatment of each condition is made more problematic by the presence of the other. We review the evidence-based treatment strategies and discuss the common problems faced by physicians when treating patients with both conditions. This article forms a comprehensive overview of a fascinating intersection between two common diseases.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McMurray, Professor John and Petrie, Professor John and Petrie, Professor Mark
Authors: MacDonald, M.R., Petrie, M.C., Hawkins, N.M., Petrie, J.R., Fisher, M., McKelvie, R., Aguilar, D., Krum, H., and McMurray, J.J.V.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:European Heart Journal
Publisher:Oxford University Press
ISSN:0195-668X
ISSN (Online):1522-9645

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