Hodder, M. C., Flanagan, D. J. and Sansom, O. J. (2018) Intestinal stem cell dynamics: a story of mice and humans. Cell Stem Cell, 22(6), pp. 785-787. (doi: 10.1016/j.stem.2018.05.005) (PMID:29859166)
|
Text
163870.pdf - Accepted Version Available under License Creative Commons Attribution Non-commercial No Derivatives. 408kB |
Abstract
Stem cell dynamics define the probability of accumulating mutations within the intestinal epithelium. In this issue of Cell Stem Cell, Nicholson et al. (2018) report that human intestinal stem cell dynamics differ significantly from those of mice and establish that oncogenic mutations are more likely to expand; therefore, "normal" epithelium may carry multiple mutations.
Item Type: | Articles |
---|---|
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Sansom, Professor Owen and Hodder, Michael |
Authors: | Hodder, M. C., Flanagan, D. J., and Sansom, O. J. |
College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
Journal Name: | Cell Stem Cell |
Publisher: | Elsevier (Cell Press) |
ISSN: | 1934-5909 |
ISSN (Online): | 1875-9777 |
Copyright Holders: | Copyright © 2018 Elsevier Inc. |
First Published: | First published in Cell Stem Cell 22(6): 785-787 |
Publisher Policy: | Reproduced in accordance with the publisher copyright policy |
University Staff: Request a correction | Enlighten Editors: Update this record