The genetic architecture underlying the evolution of a rare piscivorous life history form in brown trout after secondary contact and strong introgression

Jacobs, A., Hughes, M. R., Robinson, P. C., Adams, C. E. and Elmer, K. R. (2018) The genetic architecture underlying the evolution of a rare piscivorous life history form in brown trout after secondary contact and strong introgression. Genes, 9(6), 280. (doi: 10.3390/genes9060280) (PMID:29857499) (PMCID:PMC6026935)

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Abstract

Identifying the genetic basis underlying phenotypic divergence and reproductive isolation is a longstanding problem in evolutionary biology. Genetic signals of adaptation and reproductive isolation are often confounded by a wide range of factors, such as variation in demographic history or genomic features. Brown trout ( ) in the Loch Maree catchment, Scotland, exhibit reproductively isolated divergent life history morphs, including a rare piscivorous (ferox) life history form displaying larger body size, greater longevity and delayed maturation compared to sympatric benthivorous brown trout. Using a dataset of 16,066 SNPs, we analyzed the evolutionary history and genetic architecture underlying this divergence. We found that ferox trout and benthivorous brown trout most likely evolved after recent secondary contact of two distinct glacial lineages, and identified 33 genomic outlier windows across the genome, of which several have most likely formed through selection. We further identified twelve candidate genes and biological pathways related to growth, development and immune response potentially underpinning the observed phenotypic differences. The identification of clear genomic signals divergent between life history phenotypes and potentially linked to reproductive isolation, through size assortative mating, as well as the identification of the underlying demographic history, highlights the power of genomic studies of young species pairs for understanding the factors shaping genetic differentiation.

Item Type:Articles
Keywords:Adaptation, ferox trout, genomic divergence.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Jacobs, Arne and HUGHES, Martin and Elmer, Dr Kathryn and Adams, Professor Colin
Authors: Jacobs, A., Hughes, M. R., Robinson, P. C., Adams, C. E., and Elmer, K. R.
College/School:College of Arts > School of Culture and Creative Arts > History of Art
Journal Name:Genes
Publisher:MDPI
ISSN:2073-4425
ISSN (Online):2073-4425
Published Online:31 May 2018
Copyright Holders:Copyright © 2018 The Authors
First Published:First published in Genes 9(6): 280
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
612331GEN ECOL ADAPT: Adaptation genomics of trophic polymorphismKathryn ElmerEuropean Commission (EC)321999RI BIODIVERSITY ANIMAL HEALTH & COMPMED
489201IBIS (SCENE 2)Colin AdamsEuropean Commission (EC)2589RI BIODIVERSITY ANIMAL HEALTH & COMPMED