Associations of dietary protein intake with fat free mass and grip strength: cross-sectional study in 146,816 UK Biobank participants

Celis-Morales, C.A. et al. (2018) Associations of dietary protein intake with fat free mass and grip strength: cross-sectional study in 146,816 UK Biobank participants. American Journal of Epidemiology, 187(11), pp. 2405-2414. (doi:10.1093/aje/kwy134) (PMID:29961893)

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Abstract

Adequate dietary protein intake is important for the maintenance of fat-free mass (FFM) and muscle strength: optimal requirements remain unknown. The aim of the current study was to explore the associations of protein intake with FFM and grip strength. We used baseline data from the UK Biobank (146,816 participants aged 40-69 years with data collected 2007-2010 across the UK) to examine the associations of protein intake with FFM and grip strength. Protein intake was positively associated with FFM (men 5.1% [95% CI: 5.0; 5.2] and women 7.7% [95% CI: 7.7; 7.8]) and grip strength (men 0.076 kg/kg [95% CI: 0.074; 0.078] and women 0.074 kg/kg [95% CI: 0.073; 0.076]) per 0.5 grams per kg body mass per day (g/kg/day) increment in protein intake. FFM and grip strength were higher with higher intakes across the full range of intakes, i.e. highest in those reporting consuming > 2.0 g/grams per kg/day independently of socio-demographics, other dietary measures, physical activity and comorbidities. FFM and grip strength were lower with age, but this association did not differ by protein intake categories (P > 0.05). Current recommendation for all adults (40-69 years) for protein intake (0.8 grams per kg body mass per day) may need to be increased to optimise FFM and grip strength.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Celis, Dr Carlos and Gray, Dr Stuart and Gill, Professor Jason and Lean, Professor Michael and Welsh, Dr Paul and Iliodromiti, Dr Stamatina and Anderson, Dr Jana and Pell, Professor Jill and Mackay, Dr Daniel and Steell, Mr Lewis and Petermann, Mrs Fanny and Sattar, Professor Naveed and Lyall, Dr Donald
Authors: Celis-Morales, C.A., Petermann, F., Steell, L., Anderson, J., Welsh, P., Mackay, D.F., Iliodromiti, S., Lyall, D.M., Lean, M.E., Pell, J.P., Sattar, N., Gill, J.M.R., and Gray, S.R.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Public Health
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:American Journal of Epidemiology
Publisher:Oxford University Press
ISSN:0002-9262
ISSN (Online):1476-6256
Published Online:29 June 2018
Copyright Holders:Copyright © 2018 The Authors
First Published:First published in American Journal of Epidemiology 187(11): 2405-2414
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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