Bulluck, H., Dharmakumar, R., Arai, A. E., Berry, C. and Hausenloy, D. J. (2018) Cardiovascular magnetic resonance in acute ST-segment-elevation myocardial infarction: recent advances, controversies, and future directions. Circulation, 137(18), pp. 1949-1964. (doi: 10.1161/CIRCULATIONAHA.117.030693) (PMID:29712696) (PMCID:PMC5933067)
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Abstract
Although mortality after ST-segment elevation myocardial infarction (MI) is on the decline, the number of patients developing heart failure as a result of MI is on the rise. Apart from timely reperfusion by primary percutaneous coronary intervention, there is currently no established therapy for reducing MI size. Thus, new cardioprotective therapies are required to improve clinical outcomes after ST-segment-elevation MI. Cardiovascular magnetic resonance has emerged as an important imaging modality for assessing the efficacy of novel therapies for reducing MI size and preventing subsequent adverse left ventricular remodeling. The recent availability of multiparametric mapping cardiovascular magnetic resonance imaging has provided new insights into the pathophysiology underlying myocardial edema, microvascular obstruction, intramyocardial hemorrhage, and changes in the remote myocardial interstitial space after ST-segment-elevation MI. In this article, we provide an overview of the recent advances in cardiovascular magnetic resonance imaging in reperfused patients with ST-segment-elevation MI, discuss the controversies surrounding its use, and explore future applications of cardiovascular magnetic resonance in this setting.
| Item Type: | Articles |
|---|---|
| Keywords: | ST elevation myocardial infarction, hemorrhage, magnetic resonance imaging, percutaneous coronary intervention. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Berry, Professor Colin |
| Authors: | Bulluck, H., Dharmakumar, R., Arai, A. E., Berry, C., and Hausenloy, D. J. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health |
| Journal Name: | Circulation |
| Publisher: | American Heart Association |
| ISSN: | 0009-7322 |
| ISSN (Online): | 1524-4539 |
| Published Online: | 30 April 2018 |
| Copyright Holders: | Copyright © 2018 American Heart Association, Inc. |
| First Published: | First published in Circulation 137(18):1949-1964 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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