Mating patterns in malaria parasite populations of Papua New Guinea

Paul, R.E., Packer, M.J., Walmsley, M., Lagog, M., Ranford-Cartwright, L.C. , Paru, R. and Day, K.P. (1995) Mating patterns in malaria parasite populations of Papua New Guinea. Science, 269(5231), pp. 1709-1711. (doi: 10.1126/science.7569897) (PMID:7569897)

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Abstract

Description of the genetic structure of malaria parasite populations is central to an understanding of the spread of multiple-locus drug and vaccine resistance. The Plasmodium falciparum mating patterns from madang, Papua New Guinea, where intense transmission of malaria occurs, are described here. A high degree of inbreeding occurs in the absence of detectable linkage disequilibrium. This contrasts with other studies, indicating that the genetic structure of malaria parasite populations is neither clonal nor panmictic but will vary according to the transmission characteristics of the region.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Ranford-Cartwright, Dr Lisa
Authors: Paul, R.E., Packer, M.J., Walmsley, M., Lagog, M., Ranford-Cartwright, L.C., Paru, R., and Day, K.P.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Science
Publisher:American Association for the Advancement of Science
ISSN:0036-8075
ISSN (Online):1095-9203

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